Family MSM Dosing
Guide

This Family Methylsulfonylmethane Dosing Resource is written for those who believe in making informed decisions based on the science, the reported experience of clinicians, and their own experience of what works for them.

We here at Cellular Medicines suggest the following daily intakes of methylsulfonlymethane based on our experience in dosing methylsulfonlymethane and the scientific literature. 

Adult: 2400-4800 mg methylsulfonlymethane (equating to 30-60 ml of our methylsulfonlymethane supplements)
Child (15 yr+): 2400-3200 mg methylsulfonlymethane (equating to 30-45 ml of our methylsulfonlymethane supplements)
Child (4-14 yr): 1400 mg methylsulfonlymethane (equating to 15 ml of our methylsulfonlymethane supplements)

Pregnancy and breast-feeding do not affect the above recommendations.

It is important that you read the following precautions regarding the detoxification effect and the drug/nutrient-amplification effect of taking methylsulfonlymethane.

There are no known toxicological effects or dosage limits when taking methylsulfonlymethane, which in itself is a naturally occurring substance found in food. In that sense, methylsulfonlymethane is one of the safest therapeutics available.

However, there are two important considerations in deciding the dosage of methylsulfonlymethane, namely the detoxification effect and the drug/nutrient-amplification effect of taking methylsulfonlymethane.

The detoxification effect of methylsulfonlymethane cannot be overstated. Although we want to detoxify our bodies from a wide range of toxins, such as heavy metals, we need to detoxify at a moderate rate. We must therefore start at a small daily dose and increase the daily dose gradually, no matter how good the methylsulfonlymethane is making us look and feel.

Specifically, detoxification involves the release of toxins from cells in which they have been stored for years if not decades. A rapid release of those toxins can cause splitting headaches and other uncomfortable symptoms.

We therefore recommend the following initial daily dose of methylsulfonlymethane.

Initial daily dose for first 2 days (all ages): 1400 mg methylsulfonlymethane (which equates to 15 ml of any of our methylsulfonlymethane supplements (MSM-BEAUTY, MSM-ANTIFLAM, Asthmax, DetoxPlus).

Then increase the daily dose gradually over a few days. Typical long-term daily doses are as follows.

If a headache occurs, drink plenty of water, cease use until 24 hours after headache disappears and then recommence at half the previous dose.

We do not give recommended dosages for children younger than 4 years of age because it is difficult for very young children to communicate their discomfort from detoxification.

We next look at the drug/nutrient-amplification effect of taking methylsulfonlymethane. Methylsulfonlymethane increases the permeability of cells, making it easier for drugs and nutrients to enter the cells. This means that the effects of dietary supplements and drugs can be amplified by taking methylsulfonlymethane. This is usually a good thing in the case of nutrients and dietary supplements, whereas it is something to keep an eye on in the case of medications; i.e., you may want to lower your medication dose. Your doctor is unlikely to know about the effect of methylsulfonlymethane on medications because few doctors are knowledgable about or trained in nutrition. We therefore advise you to start on a low dose of methylsulfonlymethane and monitor the effect.